David Norman Caplan, M.D.,C.M., Ph.D.

Title  Professor of Neurology

Institution Massachusetts General Hospital

Department Neurology

Address Massachusetts General Hospital

Neuropsychology, Suite 340

175 Cambridge St.

Boston MA 02114

Phone 617/726-3274

Fax 617/724-7836

Email caplan@helix.mgh.harvard.edu

 

Research (Most Recent)

1.R56AG049733 (CAPLAN, DAVID NORMAN) Sep 30, 2015 - Aug 31, 2016

NIH/NIA

Effects of age-related declines in working memory on syntactic comprehension

Role: Principal Investigator

2.R01DC011032 (CAPLAN, DAVID NORMAN) Jun 1, 2010 - May 31, 2014

NIH/NIDCD

Spatiotemporal Neuroimaging of Situated Sentence Comprehension

Role: Principal Investigator

3.R01DC005391 (CAPLAN, DAVID NORMAN) Jan 27, 2003 - Dec 31, 2007

NIH/NIDCD

Sources of rCBF Effects in Syntactic Comprehension

Role: Principal Investigator

4.R01DC004608 (CAPLAN, DAVID NORMAN) Aug 1, 2000 - Jul 31, 2005

NIH/NIDCD

AN INVESTIGATION OF THE TRACE DELETION HYPOTHESIS

Role: Principal Investigator

5.R01DC002146 (CAPLAN, DAVID NORMAN) Feb 1, 1996 - Sep 14, 2007

NIH/NIDCD

Functional Neuroimaging Studies of Syntactic Comprehension

Role: Principal Investigator

 

Bibliographic

Greenberg J, Mace RA, Funes CJ, Silverberg ND, Iverson GL, Caplan DN, Vranceanu AM. Pain Catastrophizing and Limiting Behavior Mediate the Association Between Anxiety and Postconcussion Symptoms. Psychosomatics. 2020 Jan - Feb; 61(1):49-55. PMID: ****3327.

Smith KM, Caplan DN. Communication impairment in Parkinson's disease: Impact of motor and cognitive symptoms on speech and language. Brain Lang. 2018 10; 185:38-46. PMID: ****2448.

Hoover EL, Caplan DN, Waters GS, Carney A. Communication and quality of life outcomes from an interprofessional intensive, comprehensive, aphasia program (ICAP). Top Stroke Rehabil. 2017 03; 24(2):82-90. PMID: ****6043.

Gow DW, Caplan DN. New levels of language processing complexity and organization revealed by granger causation. Front Psychol. 2012; 3:506. PMID: ****3611.

Caplan D. Experimental design and interpretation of functional neuroimaging studies of cognitive processes. Hum Brain Mapp. 2009 Jan; 30(1):59-77. PMID: 1****9122.

Caplan D, Stanczak L, Waters G. Syntactic and thematic constraint effects on blood oxygenation level dependent signal correlates of comprehension of relative clauses. J Cogn Neurosci. 2008 Apr; 20(4):643-56. PMID: 1****2788.

Caplan D, Chen E, Waters G. Task-dependent and task-independent neurovascular responses to syntactic processing. Cortex. 2008 Mar; 44(3):257-75. PMID: 1****7556.

Caplan D, Waters G, Dede G, Michaud J, Reddy A. A study of syntactic processing in aphasia I: behavioral (psycholinguistic) aspects. Brain Lang. 2007 May; 101(2):103-50. PMID: 1****9989.

Caplan D, Waters G, Kennedy D, Alpert N, Makris N, Dede G, Michaud J, Reddy A. A study of syntactic processing in aphasia II: neurological aspects. Brain Lang. 2007 May; 101(2):151-77. PMID: 1****7366.

Caplan D. Aphasic deficits in syntactic processing. Cortex. 2006 Aug; 42(6):797-804. PMID: 1****1582.

Kuperberg GR, Lakshmanan BM, Caplan DN, Holcomb PJ. Making sense of discourse: an fMRI study of causal inferencing across sentences. Neuroimage. 2006 Oct 15; 33(1):343-61. PMID: 1****6436.

Chen E, West WC, Waters G, Caplan D. Determinants of bold signal correlates of processing object-extracted relative clauses. Cortex. 2006 May; 42(4):591-604. PMID: 1****1269.

Caplan D. Why is Broca's area involved in syntax? Cortex. 2006 May; 42(4):469-71. PMID: 1****1251.

Caplan D, Chen E. Using fMRI to discover cognitive operations. Cortex. 2006 Apr; 42(3):393-5; discussion 422-7. PMID: 1****1045.

Kuperberg GR, Kreher DA, Sitnikova T, Caplan DN, Holcomb PJ. The role of animacy and thematic relationships in processing active English sentences: evidence from event-related potentials. Brain Lang. 2007 Mar; 100(3):223-37. PMID: 1****6247.

Schmahmann JD, Caplan D. Cognition, emotion and the cerebellum. Brain. 2006 Feb; 129(Pt 2):290-2. PMID: 1****4422.

Caplan D, DeDe G, Brownell H. Effects of syntactic features on sentence-picture matching in Broca's aphasics: a reply to Drai and Grodzinksy (2005). Brain Lang. 2006 Feb; 96(2):129-34; discussion 157-70. PMID: 1****4680.

Waters G, Caplan D. The relationship between age, processing speed, working memory capacity, and language comprehension. Memory. 2005 Apr-May; 13(3-4):403-13. PMID: 1****2262.

Doherty CP, West WC, Dilley LC, Shattuck-Hufnagel S, Caplan D. Question/statement judgments: an fMRI study of intonation processing. Hum Brain Mapp. 2004 Oct; 23(2):85-98. PMID: 1****0931.

Rigalleau F, Caplan D, Baudiffier V. New arguments in favour of an automatic gender pronominal process. Q J Exp Psychol A. 2004 Jul; 57(5):893-933. PMID: 1****4122.

Rigalleau F, Baudiffier V, Caplan D. Comprehension of sentences with stylistic inversion by French aphasic patients. Brain Lang. 2004 Apr; 89(1):142-56. PMID: 1****0246.

Caplan D, Moo L. Cognitive conjunction and cognitive functions. Neuroimage. 2004 Feb; 21(2):751-6. PMID: 1****0578.

Waters GS, Caplan D. Verbal working memory and on-line syntactic processing: evidence from self-paced listening. Q J Exp Psychol A. 2004 Jan; 57(1):129-63. PMID: 1****1007.

Waters GS, Caplan D. The reliability and stability of verbal working memory measures. Behav Res Methods Instrum Comput. 2003 Nov; 35(4):550-64. PMID: 1****8499.

Kuperberg GR, Sitnikova T, Caplan D, Holcomb PJ. Electrophysiological distinctions in processing conceptual relationships within simple sentences. Brain Res Cogn Brain Res. 2003 Jun; 17(1):117-29. PMID: 1****3198.

Caplan D, Waters G, Alpert N. Effects of age and speed of processing on rCBF correlates of syntactic processing in sentence comprehension. Hum Brain Mapp. 2003 Jun; 19(2):112-31. PMID: 1****8535.

Waters G, Caplan D, Alpert N, Stanczak L. Individual differences in rCBF correlates of syntactic processing in sentence comprehension: effects of working memory and speed of processing. Neuroimage. 2003 May; 19(1):101-12. PMID: 1****1730.

Hoen M, Golembiowski M, Guyot E, Deprez V, Caplan D, Dominey PF. Training with cognitive sequences improves syntactic comprehension in agrammatic aphasics. Neuroreport. 2003 Mar 03; 14(3):495-9. PMID: 1****4511.

Waters G, Caplan D, Yampolsky S. On-line syntactic processing under concurrent memory load. Psychon Bull Rev. 2003 Mar; 10(1):88-95. PMID: 1****7494.

Kuperberg GR, Holcomb PJ, Sitnikova T, Greve D, Dale AM, Caplan D. Distinct patterns of neural modulation during the processing of conceptual and syntactic anomalies. J Cogn Neurosci. 2003 Feb 15; 15(2):272-93. PMID: 1****6064.

Caplan D, Waters G. On-line syntactic processing in aphasia: studies with auditory moving window presentation. Brain Lang. 2003 Feb; 84(2):222-49. PMID: 1****0913.

Chee MW, Caplan D. Face encoding and psychometric testing in healthy dextrals with right hemisphere language. Neurology. 2002 Dec 24; 59(12):1928-34. PMID: 1****9485.

Waters G, Caplan D. Working memory and online syntactic processing in Alzheimer's disease: studies with auditory moving window presentation. J Gerontol B Psychol Sci Soc Sci. 2002 Jul; 57(4):P298-311. PMID: 1****4781.

Chee MW, Hon NH, Caplan D, Lee HL, Goh J. Frequency of concrete words modulates prefrontal activation during semantic judgments. Neuroimage. 2002 May; 16(1):259-68. PMID: 11969333.

Yampolsky S, Waters G, Caplan D, Matthies M, Chiu P. Effects of acoustic degradation on syntactic processing: implications for the nature of the resource system used in language processing. Brain Cogn. 2002 Mar-Apr; 48(2-3):617-25. PMID: 1****0518.

Caplan D, Vijayan S, Kuperberg G, West C, Waters G, Greve D, Dale AM. Vascular responses to syntactic processing: event-related fMRI study of relative clauses. Hum Brain Mapp. 2002 Jan; 15(1):26-38. PMID: 11747098.

Caplan D. Functional neuroimaging studies of syntactic processing. J Psycholinguist Res. 2001 May; 30(3):297-320. PMID: 11523276.

Caplan D. The measurement of chance performance in aphasia, with specific reference to the comprehension of semantically reversible passive sentences: a note on issues raised by Caramazza, Capitani, Rey, and Berndt (2001) and Drai, Grodzinsky, and Zurif (2001). Brain Lang. 2001 Feb; 76(2):193-201. PMID: 11254258.

Caplan D. Language-related cortex in deaf individuals: functional specialization for language or perceptual plasticity? Proc Natl Acad Sci U S A. 2000 Dec 05; 97(25):13476-7. PMID: 11106391.

Caplan D, Alpert N, Waters G, Olivieri A. Activation of Broca's area by syntactic processing under conditions of concurrent articulation. Hum Brain Mapp. 2000 Feb; 9(2):65-71. PMID: 10680763.

Caplan D, Waters GS. Verbal working memory and sentence comprehension. Behav Brain Sci. 1999 Feb; 22(1):77-94; discussion 95-126. PMID: 11301522.

Caplan D, Alpert N, Waters G. Effects of syntactic structure and propositional number on patterns of regional cerebral blood flow. J Cogn Neurosci. 1998 Jul; 10(4):541-52. PMID: ****2683.